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Lorraine J Gudas Selected Research

Interferons

9/2007Phase 1/2 clinical trial of interferon alpha2b and weekly liposome-encapsulated all-trans retinoic acid in patients with advanced renal cell carcinoma.
9/2002Phase I trial of interferon alpha2b and liposome-encapsulated all-trans retinoic acid in the treatment of patients with advanced renal cell carcinoma.

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Lorraine J Gudas Research Topics

Disease

50Neoplasms (Cancer)
01/2023 - 02/2002
18Carcinogenesis
01/2020 - 03/2002
15Renal Cell Carcinoma (Grawitz Tumor)
12/2023 - 09/2002
10Prostatic Neoplasms (Prostate Cancer)
01/2023 - 03/2002
9Urinary Bladder Neoplasms (Bladder Cancer)
12/2013 - 05/2004
9Carcinoma (Carcinomatosis)
07/2013 - 03/2002
7Acute Promyelocytic Leukemia
01/2022 - 11/2007
6Kidney Neoplasms (Kidney Cancer)
01/2023 - 10/2003
5Squamous Cell Carcinoma of Head and Neck
04/2024 - 11/2013
5Liver Diseases (Liver Disease)
07/2023 - 01/2019
5Breast Neoplasms (Breast Cancer)
01/2011 - 11/2002
4Alcoholism (Alcohol Abuse)
03/2022 - 11/2013
4Obesity
12/2021 - 01/2009
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2015 - 01/2004
4Teratocarcinoma
07/2010 - 03/2003
3Inflammation (Inflammations)
02/2024 - 01/2019
3Fibrosis (Cirrhosis)
02/2024 - 11/2021
3Ischemia
01/2023 - 01/2018
3Adenocarcinoma
01/2022 - 03/2002
3Leukemia
01/2022 - 04/2013
3Neoplasm Metastasis (Metastasis)
12/2021 - 08/2004
3Non-alcoholic Fatty Liver Disease
12/2021 - 10/2016
3Keratomalacia
01/2020 - 10/2010
3Esophageal Squamous Cell Carcinoma
09/2015 - 06/2014
3Lymphatic Metastasis
12/2013 - 12/2011
2Kidney Diseases (Kidney Disease)
01/2023 - 01/2012
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2023 - 10/2018
2Fatty Liver
03/2022 - 12/2021
2Hypoxia (Hypoxemia)
11/2021 - 01/2016
2Heart Failure
11/2021 - 01/2018
2Wilms Tumor (Wilm's Tumor)
10/2018 - 02/2013
2Mouth Neoplasms (Oral Cancer)
08/2015 - 10/2010
2Vitamin A Deficiency
01/2015 - 12/2005
2Colonic Neoplasms (Colon Cancer)
06/2013 - 04/2013
2Colorectal Neoplasms (Colorectal Cancer)
06/2013 - 04/2013
1Lymphoma (Lymphomas)
04/2024
1Mitochondrial Diseases (Mitochondrial Disease)
02/2024

Drug/Important Bio-Agent (IBA)

27Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2022 - 02/2002
26RetinoidsIBA
01/2023 - 02/2002
23Proteins (Proteins, Gene)FDA Link
04/2024 - 03/2003
19Vitamin A (Retinol)FDA LinkGeneric
07/2023 - 02/2002
13Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
02/2024 - 06/2003
13Messenger RNA (mRNA)IBA
10/2022 - 05/2004
9lecithin-retinol acyltransferaseIBA
11/2020 - 03/2002
7CarcinogensIBA
09/2015 - 01/2004
6Androgen Receptors (Androgen Receptor)IBA
01/2023 - 08/2004
6AndrogensIBA
10/2022 - 12/2011
6RNA (Ribonucleic Acid)IBA
10/2022 - 03/2003
6Histone Deacetylase InhibitorsIBA
10/2020 - 03/2005
6Transcription Factors (Transcription Factor)IBA
01/2019 - 11/2003
5MethyltransferasesIBA
10/2022 - 03/2005
54- (4- (2- (n- butoxy)ethoxy)- 5- methylthiazol- 2- yl)- 2- fluorobenzoic acidIBA
12/2021 - 10/2016
5AntibodiesIBA
06/2013 - 10/2003
5Retinyl EstersIBA
03/2009 - 03/2002
4Biomarkers (Surrogate Marker)IBA
04/2024 - 04/2005
4Lysine (L-Lysine)FDA Link
01/2023 - 12/2011
4Polycomb Repressive Complex 2IBA
12/2021 - 04/2013
4Ethanol (Ethyl Alcohol)IBA
01/2021 - 03/2015
4Histones (Histone)IBA
08/2015 - 03/2005
4DNA (Deoxyribonucleic Acid)IBA
01/2011 - 06/2003
4ParaffinIBA
11/2009 - 10/2003
4EnzymesIBA
11/2006 - 03/2002
3Valproic Acid (Depakote)FDA LinkGeneric
01/2022 - 03/2005
3Small Interfering RNA (siRNA)IBA
01/2021 - 04/2013
3LipidsIBA
01/2021 - 11/2011
34-Nitroquinoline-1-oxide (4 Nitroquinoline 1 oxide)IBA
08/2015 - 11/2013
3Retinoid X Receptors (Retinoid X Receptor)IBA
06/2014 - 11/2003
3Estrogen ReceptorsIBA
07/2013 - 11/2002
3retinoic acid receptor betaIBA
12/2009 - 03/2004
3Liposomes (Liposome)IBA
09/2007 - 09/2002
2TamoxifenFDA LinkGeneric
02/2024 - 07/2013
2Electron Transport Complex I (NADH-CoQ Reductase)IBA
12/2023 - 01/2016
2CholesterolIBA
12/2023 - 11/2003
26-methyladenineIBA
10/2022 - 01/2022
2FenretinideIBA
01/2022 - 01/2021
2Hormones (Hormone)IBA
01/2022 - 06/2013
2AntioxidantsIBA
11/2021 - 01/2011
2ErbB Receptors (EGF Receptor)IBA
11/2020 - 01/2004
2Isotretinoin (Accutane)FDA LinkGeneric
10/2020 - 10/2003
2Histone Deacetylases (Histone Deacetylase)IBA
10/2020 - 10/2008
2VorinostatFDA Link
10/2020 - 10/2008
2Bexarotene (LGD1069)FDA Link
01/2019 - 06/2014
2Cyclin D1IBA
12/2013 - 10/2010
2Retinoic Acid 4-Hydroxylase (CYP26B1)IBA
10/2013 - 11/2007
2Estrogens (Estrogen)FDA Link
07/2013 - 01/2011
2Histone MethyltransferasesIBA
06/2013 - 04/2013
23-deazaneplanocinIBA
06/2013 - 04/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 06/2013
2GlycogenIBA
05/2013 - 11/2011
2retinol dehydrogenaseIBA
01/2012 - 02/2002
2Bromodeoxyuridine (BrdU)IBA
10/2010 - 01/2004
2DecitabineFDA Link
12/2009 - 03/2005
2LecithinsIBA
11/2007 - 05/2004
2InterferonsIBA
09/2007 - 09/2002
1Polycomb Repressive Complex 1IBA
04/2024
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2024

Therapy/Procedure

22Therapeutics
01/2023 - 09/2002
4Drug Therapy (Chemotherapy)
01/2022 - 01/2011
3Cystectomy
07/2013 - 08/2004
2Chemoprevention
01/2011 - 01/2004